Review Article

A National Consensus on Hematopoietic Stem Cell Transplantation for Patients with Inborn Errors of Immunity

Abstract

At present, a national consensus on hematopoietic stem cell transplantation (HSCT) for patients with inborn errors of immunity (IEI) is lacking. This consensus is written based on a combination of scientific literature and comments from the expert panel of Iranian immunologists. We formed a panel of clinical immunologists at a meeting titled “Second Meeting on the Diagnosis of IEI by IEI Experts” to receive their comments in this field. All authors reviewed and agreed on the current consensus. This consensus guideline provides recommendations on donor selection, stem cell source, conditioning regimen, mobilization and collection, stem cell infusion, engraftment and chimerism assessment, and post-transplant care for patients with IEI. The current recommendations reflect Iranian practice and do not necessarily represent global preferences.

IssueVol 9, No 1 (2026); in press QRcode
SectionReview Article
 
Keywords
Consensus Hematopoietic Stem Cell Transplantation HSCT Inborn Errors of Immunity IEI

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Yazdani R, Abdolahzadeh S, Aghajani M, Ahmadi M, Alavi-Moghaddam M, Arshi S, Asarehzadegan Dezfouli M, Asgharyan M, Ashournia P, Askarisarvestani A, Assari R, Badiee H, Bahrami S, Behfar M, Behniafard N, Chavoshzadeh Z, Choroom Kheirabadi M, Daneshmandi Z, Bemanian MH, Cheraghi T, Darabi K, Darougar S, Ebrahimi S, Eslamian G, Esmaeilbeig M, Fallahpour M, Faraji N, Farzadmanesh S, HajiAbbasi Someesaraie K, Kalantari A, Karimizadeh M, Kaviani E, Mesdaghi M, Marjani M, Modaresi M, Mohammadzadeh I, Movahedi M, Movahedi M, Moosavian M, Nabavi M, Norouzi-Barough L, Razaghian A, Shariat M, Seraj S, Seyedi S, Seyedsalehi S, Shafiei A, Shahraki Ghadimi Z, Shakerian B, Sharafian S, Shokri S, Tavakol M, Vosughi Motlagh A, Rezaei N. A National Consensus on Hematopoietic Stem Cell Transplantation for Patients with Inborn Errors of Immunity. Immunol Genet J. 2026;9(1).