Original Article

Hematological and Coagulation Factors in Term and Preterm Newborns of Mothers With Pre-eclampsia

Abstract

Objective: Pre-eclampsia (preE) is pregnancy-induced hypertension affecting a significant proportion of
pregnant women worldwide and can cause detrimental effects on the mother and newborn. Recognition of
contributing factors of health in neonates with pre-eclamptic mothers is important to reduce the burden of
the problem. The aim of the study was to determine the hematologic and coagulation factors in term and
preterm neonates born to mothers with pre-eclampsia.


Method and Materials: In this observational cross-sectional comparative study, 104 neonates born to
mothers with pre-eclampsia in Imam-Hossein Hospital from 2018 to 2021 were enrolled. The neonates
were divided into term and preterm groups according to the gestational age of the mothers. Maternal and
fetal parameters of neonates were collected. The hematologic and coagulation factors were recorded and
compared.


Results: The finding of the study demonstrated that the mean leukocyte ( P=0.030), hemoglobin ( P=0.0001),
and platelet ( P=0.0001) were significantly higher in term neonates. The mean PT ( P=0.003), PPT ( P=0.001),
and INR ( P=0.003) were significantly higher in preterm cases.


Conclusion: Totally, according to the obtained results it may be concluded that CBC indexes and
coagulopathy in term and preterm neonates born to mothers with pre-eclampsia are significantly different.

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IssueVol 5, No 4 (2022) QRcode
SectionOriginal Article
DOI https://doi.org/10.18502/igj.v5i4.16179
Keywords
Pre-eclampsia Neonatal Preterm Hematologic Factors
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How to Cite
1.
Barzamini S, Barzamini R, Taslimi Taleghani N. Hematological and Coagulation Factors in Term and Preterm Newborns of Mothers With Pre-eclampsia. Immunol Genet J. 2022;5(4):149-153.