Tehran University of Medical Sciences Immunology and Genetics Journal 2645-4831 7 3 2024 09 22 87 94 Klara Aziz Department of Cell, Molecular, and Developmental Biology, University of California, Riverside, CA, USA Parnian Jabbari Department of Cell, Molecular, and Developmental Biology, University of California, Riverside, CA, USA 2025 02 16 2025 02 16 It has been more than six decades since Artificial Intelligence (AI) was introduced to outperform humans in accuracy and speed. Ever since, many algorithms have been developed that gained success in fulfilling the claims of AI. Their high speed and accuracy have made them perfect candidates for substituting humans in many settings. Even though AI has changed the face of many industries, its application in some others is still a subject of debate. Besides AI, which, over decades, has changed the face of industries for good, there is another phenomenon that has changed it: the novel coronavirus (COVID-19) pandemic. Unlike AI, this pandemic has changed every aspect of human life. Due to its fast spread through human contact, stay-inshelter orders have been placed to slow the person-to-person transmission. This is a source of concern for industries as many of them may fade away due to the pandemic. However, there is one industry at risk of burning out rather than fading away: the healthcare industry. Limited resources, on the one hand, and increased demand, on the other hand, have made the healthcare industry one of the main victims of the pandemic. Emergency departments are flooded with patients, yet non-emergent medical services have been nearly shut down. Therefore, solutions are sought to help both lighten the burden on emergency departments and facilitate providing non-emergent medical services. AI and automated systems can be the key to such solutions. They have proved their efficacy in many instances in the healthcare industry, from emergency department triage to assisting surgeries. Thus far, their widespread use has been halted due to legal and ethical debates. However, the COVID-19 pandemic can be a turning point in the integration of AI into the healthcare system, just as improving AI integration with healthcare can be a turning point in this pandemic. Herein, we overview how AI can help deliver non-emergent medical services during the pandemic and possibly thereafter https://igj.tums.ac.ir/index.php/igj/article/view/177 https://igj.tums.ac.ir/index.php/igj/article/download/177/148